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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (379 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
ADI32111.1
KEGG: dat:HRM2_41100 PorB3; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
    
 0.934
ADI32110.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.920
ADI32129.1
PFAM: Thiolase; KEGG: gur:Gura_4354 thiolase.
  
 
 0.882
ADI31287.1
PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: scl:sce9060 NADH dehydrogenase (ubiquinone).
  
 0.876
ADI31286.1
KEGG: nse:NSE_0566 NADH dehydrogenase subunit D; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; Belongs to the complex I 49 kDa subunit family.
  
 
 0.865
ADI31488.1
KEGG: rme:Rmet_4362 CoA-binding; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein.
    
 0.846
ADI32312.1
PFAM: ATP-grasp domain protein; KEGG: dma:DMR_20040 CoA-binding domain protein.
    
 0.841
ADI32104.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0325 thiamine pyrophosphate binding domain-containing protein.
    
 0.840
ADI32105.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ppd:Ppro_0324 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
    
 0.840
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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