Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31504.1PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: pat:Patl_3544 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family. (1702 aa)    
Predicted Functional Partners:
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.603
ADI31502.1
PFAM: protein of unknown function UPF0153; KEGG: dol:Dole_0539 hypothetical protein.
       0.586
ADI31496.1
PFAM: protein of unknown function DUF58; KEGG: hch:HCH_00266 hypothetical protein.
 
    0.583
ADI31503.1
Hypothetical protein.
       0.574
ADI31390.1
SMART: serine/threonine protein kinase; KEGG: Kinase, NEK.
  
 0.558
ADI31977.1
PFAM: protein of unknown function DUF58; KEGG: sml:Smlt4486 hypothetical protein.
  
    0.513
ADI31512.1
Hypothetical protein.
  
  
 0.512
ADI31497.1
KEGG: bba:Bd2797 putative Mg chelatase; PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
       0.495
ADI31498.1
Hypothetical protein.
       0.495
ADI31976.1
Hypothetical protein.
       0.495
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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