Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31518.15 10-methylenetetrahydrofolate reductase-like protein. (234 aa)    
Predicted Functional Partners:
ADI31519.1
Methionine synthase II (cobalamin-independent)-like protein; KEGG: cha:CHAB381_1170 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
  
 0.916
ADI31705.1
KEGG: dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.709
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.549
ADI31516.1
KEGG: sfu:Sfum_0998 appr-1-p processing domain-containing protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein.
       0.520
ADI31517.1
PFAM: thiamineS protein; KEGG: bmi:BMEA_A0733 molybdopterin converting factor, subunit 1.
       0.520
ADI32560.1
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
   
  
 0.467
ADI31379.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase.
   
 
 0.465
ADI31515.1
Hypothetical protein; KEGG: sat:SYN_01902 mannosyltransferase.
  
    0.464
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 0.455
ADI31669.1
PFAM: aminotransferase class I and II; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class V; KEGG: mes:Meso_2719 aminotransferase.
  
  
 0.434
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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