STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31519.1Methionine synthase II (cobalamin-independent)-like protein; KEGG: cha:CHAB381_1170 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. (328 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.974
ADI31518.1
5 10-methylenetetrahydrofolate reductase-like protein.
  
 
 0.941
mat
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
     
 0.920
ADI32039.1
KEGG: sat:SYN_00558 methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.911
ADI31581.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cysteine synthase A; K01738 cysteine synthase A.
  
 
 0.875
ADI31410.1
KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.
  
 
 0.858
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.599
ADI31521.1
Uncharacterized metal-binding protein-like protein; KEGG: geo:Geob_1421 hypothetical protein.
       0.592
ADI32172.1
Kinase (sugar kinase superfamily)-like protein.
  
    0.589
ADI31520.1
Methionine synthase; KEGG: geo:Geob_2541 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein.
       0.579
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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