Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31523.1MATE efflux family protein; KEGG: sun:SUN_0162 sodium-driven multidrug efflux pump protein; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE. (448 aa)    
Predicted Functional Partners:
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
    0.726
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; KEGG: ajs:Ajs_2165 glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
  
  
 0.644
ADI31524.1
PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; Acetyl xylan esterase; KEGG: swp:swp_1880 peptidase S9, prolyl oligopeptidase active site region:WD40-like beta propeller.
 
     0.620
rps17
Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
 
 
 
 0.543
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
 
 
 
 0.541
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.528
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.525
rps6e
PFAM: Ribosomal protein S6e; KEGG: 40S RIBOSOMAL PROTEIN S6; K02991 small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
    
   0.492
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
   
   0.470
ADI31522.1
PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit.
       0.431
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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