Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31524.1PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S15; Acetyl xylan esterase; KEGG: swp:swp_1880 peptidase S9, prolyl oligopeptidase active site region:WD40-like beta propeller. (648 aa)    
Predicted Functional Partners:
ADI31523.1
MATE efflux family protein; KEGG: sun:SUN_0162 sodium-driven multidrug efflux pump protein; TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE.
 
     0.620
ADI31332.1
TIGRFAM: peptidase S26B, signal peptidase.
  
 
 0.611
ADI32280.1
KEGG: signal peptidase; K03100 signal peptidase I; TIGRFAM: peptidase S26B, signal peptidase; PFAM: Peptidase S24/S26A/S26B, conserved region.
  
 
 0.611
ADI32422.1
PFAM: translation initiation factor SUI1; KEGG: mmw:Mmwyl1_2203 translation initiation factor SUI1; Belongs to the SUI1 family.
    
   0.592
infB
Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
   
   0.592
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
    
   0.592
tmcA
Protein of unknown function DUF699 ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
    0.508
ADI31525.1
PFAM: protein of unknown function DUF124; KEGG: scl:sce6258 hypothetical protein.
       0.405
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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