Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31547.16-phospho 3-hexuloisomerase; KEGG: mca:MCA2738 hexulose-6-phosphate synthase/SIS domain-containing protein; TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS). (206 aa)    
Predicted Functional Partners:
ADI31443.1
PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mfa:Mfla_0250 hexulose-6-phosphate synthase.
 
 0.999
ADI32408.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
    
 0.919
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
 0.914
ADI32045.1
PFAM: peptidase M55 D-aminopeptidase; KEGG: pct:PC1_4113 peptidase M55 D-aminopeptidase.
      
 0.759
ADI31276.1
PFAM: Citrate transporter; Arsenical pump membrane protein; KEGG: dma:DMR_06440 arsenical pump membrane protein.
  
  
 0.655
ADI31548.1
PFAM: Radical SAM domain protein; KEGG: ppg:PputGB1_0113 radical SAM domain-containing protein.
       0.607
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.552
ADI31546.1
Hypothetical protein.
       0.549
ADI32559.1
TIGRFAM: ribose 5-phosphate isomerase; KEGG: sfr:Sfri_0848 ribose-5-phosphate isomerase A; PFAM: Ribose 5-phosphate isomerase.
 
  
 0.540
ADI31744.1
PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: gur:Gura_0855 nucleotidyl transferase.
  
   0.452
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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