STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31547.16-phospho 3-hexuloisomerase; KEGG: mca:MCA2738 hexulose-6-phosphate synthase/SIS domain-containing protein; TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS). (206 aa)    
Predicted Functional Partners:
ADI31443.1
PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mfa:Mfla_0250 hexulose-6-phosphate synthase.
 
 0.999
ADI32408.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
    
 0.933
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
ADI31548.1
PFAM: Radical SAM domain protein; KEGG: ppg:PputGB1_0113 radical SAM domain-containing protein.
       0.609
ADI31546.1
Hypothetical protein.
       0.548
ADI32045.1
PFAM: peptidase M55 D-aminopeptidase; KEGG: pct:PC1_4113 peptidase M55 D-aminopeptidase.
      
 0.480
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.468
ADI31907.1
PFAM: PfkB domain protein; KEGG: gbm:Gbem_2483 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
    0.442
ADI31744.1
PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: gur:Gura_0855 nucleotidyl transferase.
  
   0.425
ADI31545.1
Hypothetical protein.
       0.421
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.