Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31556.1PFAM: Fmu (Sun) domain protein; KEGG: dar:Daro_3159 Fmu (Sun)/nucleolar NOL1/Nop2p. (449 aa)    
Predicted Functional Partners:
ADI31161.1
PFAM: GTP-binding protein HSR1-related; KEGG: nucleolar GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
 
 0.754
ADI32123.1
Hypothetical protein.
  
 
 0.729
ADI32297.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: hypothetical protein.
   
 
 0.704
ADI32619.1
KEGG: nucleolar GTP-binding protein 1; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Nucleolar GTP-binding-1 domain protein.
   
 
 0.700
rps8e
KEGG: 40S ribosomal protein S8; K02995 small subunit ribosomal protein S8e; TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E.
   
 
 0.627
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.615
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.607
rpl30
KEGG: 60S RIBOSOMAL PROTEIN L7; K02937 large subunit ribosomal protein L7e; TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30.
   
 
 0.606
ADI32694.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
   
   0.600
eif6
Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
   
 
 0.575
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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