Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31569.1ABC transporter related protein; KEGG: cco:CCC13826_1791 ATP-dependent DNA helicase PcrA; PFAM: ABC transporter related; SMART: AAA ATPase. (256 aa)    
Predicted Functional Partners:
ADI31567.1
PFAM: ABC-3 protein; KEGG: ppf:Pput_1966 ABC-3 protein.
 
 
 0.986
ADI31568.1
PFAM: periplasmic solute binding protein; KEGG: bpr:GBP346_A0794 putative cation ABC transporter, periplasmic cation-binding protein.
 
  
 0.966
ADI31566.1
Putative transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein.
     
 0.770
ADI31565.1
KEGG: hypothetical protein.
       0.595
ADI31202.1
aminoacyl-tRNA synthetase class Ia; KEGG: rbe:RBE_0509 valyl-tRNA synthetase.
 
     0.501
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
     0.483
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
     0.427
rpl2
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
     0.409
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
     0.405
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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