Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31576.1PFAM: N-6 DNA methylase; KEGG: hpa:HPAG1_0892 adenine specific DNA methyltransferase. (384 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.809
ADI31575.1
Hypothetical protein.
       0.664
ADI32252.1
PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; KEGG: hypothetical protein.
  
    0.478
ADI32634.1
DNA-cytosine methyltransferase; KEGG: ngo:NGO1894 putative 5-methylcytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
   
 0.465
ADI31574.1
Hypothetical protein.
       0.450
ADI31339.1
KEGG: sml:Smlt1846B hypothetical protein; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
   
 0.439
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
 
  
 0.426
ADI31254.1
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: nam:NAMH_0956 DNA methylase.
 
   
 0.421
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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