Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ADI31602.1PFAM: metallophosphoesterase; KEGG: afw:Anae109_3653 phosphodiesterase. (248 aa)    
Predicted Functional Partners:
ADI31622.1
KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein.
  
 0.974
ADI32037.1
KEGG: hypothetical protein.
   
 0.780
ADI32314.1
PFAM: protein of unknown function ATP binding; KEGG: ATP-binding protein; K06883.
   
 0.746
ADI31623.1
Hypothetical protein.
   
 0.721
ADI31463.1
KEGG: mxa:MXAN_5915 hypothetical protein.
   
 0.664
ADI32686.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: hypothetical protein.
   
 0.664
eif2a
Translation initiation factor 2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 
 0.582
rpl14e
KEGG: hypothetical protein; K02875 large subunit ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family.
    
 0.548
ADI31318.1
GTPase or GTP-binding protein-like protein; KEGG: AAA family ATPase Grc3 (predicted); K06947.
     
  0.533
rpl40e
PFAM: Ribosomal protein L40e; KEGG: Ubiquitin/ribosomal protein CEP52; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
 0.531
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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