Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31622.1KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein. (945 aa)    
Predicted Functional Partners:
ADI31939.1
KEGG: pna:Pnap_0369 ABC transporter related; PFAM: Dual specificity protein phosphatase; SMART: Dual specificity phosphatase, subgroup, catalytic domain; Protein-tyrosine phosphatase, catalytic.
  
 0.995
ADI31942.1
KEGG: conserved hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
  
 0.988
ADI32371.1
KEGG: maq:Maqu_3834 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
  
 0.983
ADI32314.1
PFAM: protein of unknown function ATP binding; KEGG: ATP-binding protein; K06883.
   
 0.982
ADI31343.1
KEGG: hypothetical protein.
  
 0.974
ADI31602.1
PFAM: metallophosphoesterase; KEGG: afw:Anae109_3653 phosphodiesterase.
  
 0.974
ADI32291.1
Bis(5'nucleosyl)-tetraphosphatase, ApaH; KEGG: NUCLEAR SER/THR PROTEIN PHOSPHATASE PP1-1 GAMMA CATALYTIC SUBUNIT; PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase.
  
 0.974
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.969
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.943
ADI31162.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: xcc:XCC1989 molybdopterin biosynthesis protein MoeB.
   
 0.938
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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