Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADI31623.1Hypothetical protein. (57 aa)    
Predicted Functional Partners:
ADI31942.1
KEGG: conserved hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
  
 0.866
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.866
ADI31939.1
KEGG: pna:Pnap_0369 ABC transporter related; PFAM: Dual specificity protein phosphatase; SMART: Dual specificity phosphatase, subgroup, catalytic domain; Protein-tyrosine phosphatase, catalytic.
  
 0.857
ADI32371.1
KEGG: maq:Maqu_3834 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
   
 0.843
ADI31161.1
PFAM: GTP-binding protein HSR1-related; KEGG: nucleolar GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 0.837
ADI31463.1
KEGG: mxa:MXAN_5915 hypothetical protein.
    
 0.794
ADI32686.1
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: hypothetical protein.
    
 0.794
ADI32420.1
PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: hch:HCH_05059 metal-dependent hydrolase.
  
 0.768
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.768
ADI31162.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: xcc:XCC1989 molybdopterin biosynthesis protein MoeB.
   
 0.725
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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