STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31708.1PFAM: amidohydrolase; Amidohydrolase 3; KEGG: Amidohydrolase family protein. (495 aa)    
Predicted Functional Partners:
ADI31728.1
S-adenosylhomocysteine deaminase; KEGG: dal:Dalk_5014 amidohydrolase; PFAM: amidohydrolase.
  
  
 
0.931
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
 
 0.920
ADI31551.1
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: atrazine chlorohydrolase/guanine deaminase.
  
  
 
0.916
speE
Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
   
  0.909
ADI31417.1
PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3168 uridine phosphorylase.
    
 0.905
ADI31709.1
KEGG: sat:SYN_01213 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the carbamate kinase family.
       0.565
creN7
Hypothetical protein; A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils. Belongs to the Cren7 family.
       0.463
ADI31705.1
KEGG: dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.422
ADI32015.1
Hydroxymethylpyrimidine transporter CytX; KEGG: nmc:NMC2048 putative permease; TIGRFAM: hydroxymethylpyrimidine transporter CytX; PFAM: permease for cytosine/purines uracil thiamine allantoin.
  
  
 0.404
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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