STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (499 aa)    
Predicted Functional Partners:
ADI32349.1
PFAM: gamma-glutamyltranspeptidase; KEGG: pla:Plav_1569 gamma-glutamyltransferase.
    
 0.925
ADI31581.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cysteine synthase A; K01738 cysteine synthase A.
   
 0.858
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.855
ADI31669.1
PFAM: aminotransferase class I and II; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class V; KEGG: mes:Meso_2719 aminotransferase.
   
  0.831
ADI31384.1
PFAM: peptidase M24; KEGG: sat:SYN_01769 Xaa-pro dipeptidase.
 
 
 0.566
ADI31775.1
Hypothetical protein.
       0.509
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.493
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
  
  
 0.436
ADI32625.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfu:Sfum_3874 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.428
ADI31195.1
alpha-L-glutamate ligase, RimK family; KEGG: aap:NT05HA_1236 ribosomal protein S6 modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201.
  
  
 0.423
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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