STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31784.1Phosphodiesterase, MJ0936 family; KEGG: vacuolar protein sorting-associated protein; K07095; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase. (193 aa)    
Predicted Functional Partners:
ADI31783.1
Hypothetical protein.
       0.776
ADI32712.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.641
ADI31874.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.562
ADI31782.1
Mn2+dependent serine/threonine protein kinase; KEGG: abu:Abu_1820 hypothetical protein.
       0.506
ADI31781.1
PFAM: protein of unknown function DUF211; KEGG: eic:NT01EI_3508 hypothetical protein.
       0.481
ADI32328.1
MCM family protein; KEGG: hypothetical protein; K02540 minichromosome maintenance protein 2; PFAM: MCM family protein; SMART: MCM family protein; Hedgehog/intein hint domain protein; Belongs to the MCM family.
       0.447
rpl13e
Rpl13; K02873 large subunit ribosomal protein L13e; KEGG: rpl13; ribosomal protein L13; K02873 large subunit ribosomal protein L13e; Belongs to the eukaryotic ribosomal protein eL13 family.
 
     0.409
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.