Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31799.1PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bba:Bd3861 pyruvate carboxylase. (515 aa)    
Predicted Functional Partners:
ADI31595.1
KEGG: maq:Maqu_0971 oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
 
  
 0.957
ADI32059.1
KEGG: dat:HRM2_26920 BirA; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase.
 
 0.939
ADI32128.1
PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit.
 
 
 0.885
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.767
ADI32127.1
PFAM: biotin/lipoyl attachment domain-containing protein; glycine cleavage H-protein; KEGG: dal:Dalk_3023 oxaloacetate decarboxylase.
  
  
 0.595
ADI31327.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: atc:AGR_C_1817 3-oxoacyl-[acyl-carrier protein] reductase.
 
 
 0.544
ADI31800.1
Hypothetical protein.
       0.520
ADI31798.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
       0.518
ADI31801.1
KEGG: mlo:mlr1185 succinyl-diaminopimelate desuccinylase; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
       0.476
ADI32420.1
PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: hch:HCH_05059 metal-dependent hydrolase.
  
  
 0.421
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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