Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31847.1PFAM: transcriptional regulator TrmB; KEGG: dma:DMR_12570 hypothetical protein. (349 aa)    
Predicted Functional Partners:
ADI31846.1
PFAM: glycosyl transferase group 1; KEGG: sat:SYN_02626 lipopolysaccharide N-acetylglucosaminyltransferase.
       0.555
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
   
 0.502
ADI31795.1
KEGG: ypb:YPTS_3513 type II secretion system protein E; PFAM: PilT protein domain protein; SMART: Nucleotide binding protein PINc; AAA ATPase.
  
     0.493
ADI31533.1
SMART: Transcription regulator, AsnC-type; KEGG: mes:Meso_2418 AsnC family transcriptional regulator.
  
   
 0.461
ADI31956.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: azo:azo2931 hypothetical protein.
   
    0.452
ADI32496.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dds:Ddes_1666 4Fe-4S ferredoxin iron-sulfur binding domain protein.
   
    0.452
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
  
    0.440
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.420
ADI31172.1
PFAM: Protein of unknown function DUF655.
  
     0.410
ef1b
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
     0.408
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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