Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI31853.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (423 aa)    
Predicted Functional Partners:
ADI31410.1
KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.
  
 
0.944
ADI32672.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: vfi:VF_1458 threonine synthase.
  
  
 
0.923
ADI31764.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pen:PSEEN3862 threonine synthase.
  
  
 
0.917
ADI31852.1
PFAM: dihydrodipicolinate reductase; KEGG: mxa:MXAN_4674 hypothetical protein.
       0.488
ADI32594.1
Transcriptional regulator, AbrB family; KEGG: rme:Rmet_1966 homoserine dehydrogenase; TIGRFAM: transcriptional regulator, AbrB family; PFAM: amino acid-binding ACT domain protein; SpoVT/AbrB domain protein.
  
  
 0.478
ADI31379.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase.
  
  
 0.466
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.437
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.