Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31874.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (235 aa)    
Predicted Functional Partners:
ADI32625.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfu:Sfum_3874 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.900
ADI31754.1
Hypothetical protein; KEGG: sfu:Sfum_3874 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.899
ADI32195.1
Hypothetical protein.
  
 0.864
ADI32286.1
KEGG: hypothetical protein.
  
 0.864
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.650
atpB
H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
  
 
 0.633
ADI31862.1
PFAM: metallophosphoesterase; KEGG: gme:Gmet_1223 metallophosphoesterase.
  
 
 0.627
ADI31886.1
PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: gme:Gmet_2613 twin-arginine translocation pathway signal.
  
  
 0.614
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
   
 
 0.606
ADI32655.1
TIGRFAM: pyruvate kinase; KEGG: pca:Pcar_2983 pyruvate kinase; PFAM: Pyruvate kinase barrel; Belongs to the pyruvate kinase family.
   
 
 0.606
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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