Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31909.1PFAM: PP-loop domain protein; KEGG: hypothetical protein. (331 aa)    
Predicted Functional Partners:
ADI31910.1
PFAM: thiamineS protein; KEGG: gem:GM21_2934 thiamineS protein.
  
  
 0.822
ADI32679.1
KEGG: dds:Ddes_1919 tRNA methyltransferase complex GCD14 subunit; PFAM: tRNA methyltransferase complex GCD14 subunit; Methyltransferase type 11; Methyltransferase type 12; protein-L-isoaspartate(D-aspartate) O-methyltransferase.
 
  
 0.668
ADI31537.1
PFAM: PP-loop domain protein; Queuosine synthesis-like; KEGG: sfu:Sfum_0716 PP-loop domain-containing protein.
  
  
 
0.599
ADI31908.1
Putative transcriptional regulator, CopG family.
       0.590
ADI31162.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: xcc:XCC1989 molybdopterin biosynthesis protein MoeB.
  
 
 0.529
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.505
ADI31946.1
SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: histone acetyltransferase, ELP3 family; KEGG: AGAP008300-PA; K07739 elongator complex protein 3; PFAM: Radical SAM domain protein; GCN5-related N-acetyltransferase.
   
 
 0.505
ADI31914.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rlg:Rleg_6686 binding-protein-dependent transport systems inner membrane component.
 
     0.468
ADI31227.1
PFAM: tRNA pseudouridine synthase D TruD; KEGG: gur:Gura_0971 tRNA pseudouridine synthase D, TruD.
 
 
 0.463
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.458
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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