Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31928.1Acetylornithine transaminase; KEGG: sfu:Sfum_2649 aminotransferase class-III; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)    
Predicted Functional Partners:
ADI32259.1
PFAM: Pyridoxal-dependent decarboxylase; aminotransferase class V; KEGG: swd:Swoo_2007 pyridoxal-dependent decarboxylase.
  
 0.948
ADI32173.1
PFAM: Protein of unknown function DUF137.
     
  0.900
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
  
 
 0.735
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.655
ADI31380.1
PFAM: aminotransferase class V; aminotransferase class-III; KEGG: gbm:Gbem_0736 aminotransferase class V.
  
 
 0.597
ADI31246.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: bcm:Bcenmc03_5466 alcohol dehydrogenase.
 
 
 0.565
ADI31906.1
PFAM: FAD dependent oxidoreductase; KEGG: scl:sce0669 sarcosine oxidase, beta subunit.
  
  
 0.497
ADI31730.1
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: vei:Veis_2839 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
 
  
 0.488
arcB
TIGRFAM: ornithine carbamoyltransferase; KEGG: sat:SYN_02156 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region.
  
 0.481
ADI31700.1
PFAM: Cupin 2 conserved barrel domain protein; KEGG: dat:HRM2_42600 cupin domain family protein.
  
  
 0.471
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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