Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31932.1Radical SAM domain protein; KEGG: shl:Shal_0144 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB. (316 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
ADI31734.1
KEGG: smd:Smed_5507 molybdenum cofactor synthesis domain-containing protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain.
 
 
 0.923
ADI32464.1
PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198.
     
  0.900
ADI31944.1
KEGG: dal:Dalk_4696 molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain.
 
 0.831
ADI32370.1
Adenylyl cyclase CyaB; KEGG: dal:Dalk_3154 adenylate cyclase; TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase.
    
  0.814
ADI32486.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dvm:DvMF_1473 anaerobic ribonucleoside triphosphate reductase.
    
 0.811
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
  0.800
ADI31925.1
PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; KEGG: gem:GM21_2072 molybdenum cofactor synthesis domain protein.
 
 
 0.776
ADI31643.1
KEGG: mxa:MXAN_2759 molybdenum cofactor biosynthesis protein B; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain.
 
  
 0.752
ADI31482.1
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: psp:PSPPH_1124 molybdopterin converting factor, subunit 2.
 
  
 0.743
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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