Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32059.1KEGG: dat:HRM2_26920 BirA; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase. (303 aa)    
Predicted Functional Partners:
ADI31799.1
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bba:Bd3861 pyruvate carboxylase.
 
 0.939
ADI32128.1
PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit.
 
 
 0.870
ADI32060.1
PFAM: protein of unknown function UPF0153.
       0.848
ADI32061.1
TIGRFAM: cytidyltransferase-related domain protein; KEGG: dac:Daci_5608 cytidyltransferase-like protein; PFAM: cytidylyltransferase.
     
 0.787
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.742
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.596
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.552
ADI32062.1
PFAM: peptidase M50; KEGG: glo:Glov_1881 peptidase M50.
       0.519
ADI32377.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfu:Sfum_3077 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.482
ADI31395.1
KEGG: sfu:Sfum_2757 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain.
 
     0.465
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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