Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32128.1PFAM: carboxyl transferase; KEGG: mxa:MXAN_1113 propionyl-CoA carboxylase, beta subunit. (521 aa)    
Predicted Functional Partners:
ADI31799.1
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bba:Bd3861 pyruvate carboxylase.
 
 
 0.885
ADI32059.1
KEGG: dat:HRM2_26920 BirA; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase.
 
 
 0.870
ADI32129.1
PFAM: Thiolase; KEGG: gur:Gura_4354 thiolase.
  
 
 0.848
ADI32328.1
MCM family protein; KEGG: hypothetical protein; K02540 minichromosome maintenance protein 2; PFAM: MCM family protein; SMART: MCM family protein; Hedgehog/intein hint domain protein; Belongs to the MCM family.
       0.495
ADI31327.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: atc:AGR_C_1817 3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.434
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.427
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.427
ADI32130.1
Hypothetical protein.
       0.418
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
  
 
 0.401
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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