STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)    
Predicted Functional Partners:
ADI32170.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.984
ADI32172.1
Kinase (sugar kinase superfamily)-like protein.
     
 0.845
ADI32173.1
PFAM: Protein of unknown function DUF137.
     
 0.843
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.813
ADI32169.1
PFAM: Phosphomethylpyrimidine kinase.
       0.665
ADI32168.1
Hypothetical protein.
       0.649
ADI32166.1
PFAM: ABC-2 type transporter; KEGG: xfn:XfasM23_1445 ABC transporter sodium permease.
       0.540
ADI32174.1
KEGG: sat:SYN_02177 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
 
   
 0.529
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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