Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI32173.1PFAM: Protein of unknown function DUF137. (259 aa)    
Predicted Functional Partners:
ADI32172.1
Kinase (sugar kinase superfamily)-like protein.
 
  
 0.997
ADI32174.1
KEGG: sat:SYN_02177 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
 
  
 0.951
ADI32259.1
PFAM: Pyridoxal-dependent decarboxylase; aminotransferase class V; KEGG: swd:Swoo_2007 pyridoxal-dependent decarboxylase.
 
  
 0.924
ADI31928.1
Acetylornithine transaminase; KEGG: sfu:Sfum_2649 aminotransferase class-III; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.843
ADI32170.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
     
 0.705
ADI32169.1
PFAM: Phosphomethylpyrimidine kinase.
 
     0.620
ADI32319.1
PFAM: Protein of unknown function DUF54; Belongs to the UPF0201 family.
 
     0.538
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
 
     0.501
ADI32453.1
PFAM: NMD3 family protein.
 
     0.479
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (12%) [HD]