Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32177.1DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; KEGG: rcm:A1E_04790 endonuclease III; SMART: HhH-GPD family protein; iron-sulfur cluster loop. (234 aa)    
Predicted Functional Partners:
ADI32176.1
KEGG: afw:Anae109_2720 asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type.
  
  
 0.843
ADI32378.1
Hypothetical protein.
  
 
 0.763
ADI31485.1
PFAM: Xylose isomerase domain protein TIM barrel.
  
 
 0.696
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
   
 
 0.680
ADI31767.1
PFAM: ERCC4 domain protein; helix-hairpin-helix motif; KEGG: sbn:Sbal195_0376 ERCC4 domain-containing protein.
    
 
 0.578
ADI31902.1
PFAM: Beta propeller domain; KEGG: hypothetical protein.
    
 
 0.578
ADI32320.1
Dephospho-CoA kinase-like protein; KEGG: hypothetical protein; Belongs to the UPF0200 family.
  
  
 0.477
ADI31705.1
KEGG: dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.476
ADI32174.1
KEGG: sat:SYN_02177 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
     
 0.468
ADI32175.1
KEGG: ARD1B; ARD1 homolog B (S. cerevisiae); TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase.
       0.456
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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