Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32191.1TIGRFAM: translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized protein; KEGG: gur:Gura_4322 aIF-2BI family translation initiation factor; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family. (330 aa)    
Predicted Functional Partners:
ADI32190.1
PFAM: initiation factor 2B related; KEGG: hypothetical protein; K03680 translation initiation factor eIF-2B delta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 
0.989
ADI31907.1
PFAM: PfkB domain protein; KEGG: gbm:Gbem_2483 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
    
 0.919
eif2a
Translation initiation factor 2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 0.882
ADI32192.1
Hypothetical protein.
       0.879
eif2g
Protein synthesis factor GTP-binding protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.876
rbcL
Ribulose bisphosphate carboxylase, type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
 0.846
ADI32189.1
P-loop ATPase/GTPase-like protein.
       0.766
ADI32095.1
AMP phosphorylase; KEGG: tau:Tola_2482 thymidine phosphorylase; TIGRFAM: AMP phosphorylase; thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like.
 
  
 0.750
ADI31166.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: Hypothetical protein CBG06266.
   
 0.693
ADI31744.1
PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: gur:Gura_0855 nucleotidyl transferase.
   
 0.693
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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