Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htpXPFAM: peptidase M48 Ste24p; KEGG: pca:Pcar_0242 heat shock protein; Belongs to the peptidase M48B family. (367 aa)    
Predicted Functional Partners:
ADI32172.1
Kinase (sugar kinase superfamily)-like protein.
  
    0.830
ADI31558.1
PFAM: Auxin Efflux Carrier; KEGG: tgr:Tgr7_2040 auxin efflux carrier.
  
  
 0.821
ADI32228.1
Hypothetical protein.
       0.788
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.772
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
  
 0.691
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.673
ADI32129.1
PFAM: Thiolase; KEGG: gur:Gura_4354 thiolase.
   
 0.634
ADI32424.1
Agmatinase; KEGG: pub:SAR11_1329 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.
  
 
 0.619
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.618
ADI32420.1
PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: hch:HCH_05059 metal-dependent hydrolase.
  
    0.595
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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