Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI32242.1PFAM: protein of unknown function DUF82; KEGG: rme:Rmet_0174 hypothetical protein. (178 aa)    
Predicted Functional Partners:
ADI32241.1
PFAM: AMMECR1 domain protein; KEGG: dal:Dalk_3956 AMMECR1 domain protein.
       0.880
ADI32243.1
CBS domain containing protein; KEGG: pca:Pcar_0067 putative inosine monophosphate dehydrogenase; PFAM: CBS domain containing protein; SMART: CBS domain containing protein.
       0.797
ADI32244.1
Putative signal transduction protein with CBS domains; KEGG: dma:DMR_17080 hypothetical protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein.
       0.757
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.607
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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