Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
matMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (409 aa)    
Predicted Functional Partners:
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
  
  
 0.915
ADI31519.1
Methionine synthase II (cobalamin-independent)-like protein; KEGG: cha:CHAB381_1170 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
     
 0.900
ADI32634.1
DNA-cytosine methyltransferase; KEGG: ngo:NGO1894 putative 5-methylcytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
  0.900
ADI32252.1
PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; KEGG: hypothetical protein.
       0.633
ADI32453.1
PFAM: NMD3 family protein.
 
     0.478
ADI32246.1
Like-Sm ribonucleoprotein core; KEGG: U6 snRNA-associated Sm-like protein LSm6; K04796 small nuclear ribonucleoprotein; PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein.
  
    0.419
ADI32370.1
Adenylyl cyclase CyaB; KEGG: dal:Dalk_3154 adenylate cyclase; TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase.
 
     0.409
ADI31371.1
Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein.
 
     0.408
ADI32251.1
Hypothetical protein.
       0.402
ADI32638.1
Transcriptional regulator, XRE family; KEGG: SORBIDRAFT_10g023010; hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
    0.400
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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