STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI32254.1PFAM: Protein of unknown function DUF460; KEGG: wri:WRi_002780 hypothetical protein. (671 aa)    
Predicted Functional Partners:
ADI32255.1
RIO-like kinase; KEGG: hypothetical protein; K07179 RIO kinase 2; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1.
 
     0.901
ADI32641.1
PFAM: protein of unknown function DUF75.
  
     0.661
ADI32256.1
Transcriptional regulator, MarR family; KEGG: sdy:SDY_2857 hypothetical protein; PFAM: regulatory protein ArsR; regulatory protein MarR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein ArsR.
       0.567
ADI32370.1
Adenylyl cyclase CyaB; KEGG: dal:Dalk_3154 adenylate cyclase; TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase.
  
     0.561
ADI32091.1
PFAM: phosphoesterase DHHA1; KEGG: hpa:HPAG1_0405 hypothetical protein.
  
     0.526
ADI32631.1
Phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SpoVT/AbrB domain protein; KEGG: bba:Bd2221 Na/Pi-cotransporter family protein.
  
     0.505
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
  
     0.499
ADI32172.1
Kinase (sugar kinase superfamily)-like protein.
  
     0.494
ADI31391.1
KEGG: glo:Glov_0622 phosphate uptake regulator, PhoU; TIGRFAM: transcriptional regulator, AbrB family; PFAM: PhoU family protein; SpoVT/AbrB domain protein.
  
     0.443
ADI32299.1
Transcriptional regulator, XRE family; KEGG: wpi:WPa_0273 putative transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
 
     0.440
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.