| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI31582.1 | ADI32282.1 | Shell_0451 | Shell_1182 | PFAM: FG-GAP repeat protein; Pyrrolo-quinoline quinone; KEGG: hypothetical protein. | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | 0.592 |
| ADI32282.1 | ADI31582.1 | Shell_1182 | Shell_0451 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | PFAM: FG-GAP repeat protein; Pyrrolo-quinoline quinone; KEGG: hypothetical protein. | 0.592 |
| ADI32282.1 | ADI32284.1 | Shell_1182 | Shell_1184 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | 0.661 |
| ADI32282.1 | pyrH | Shell_1182 | Shell_0016 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.423 |
| ADI32282.1 | rpoK | Shell_1182 | Shell_1183 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.857 |
| ADI32282.1 | topA | Shell_1182 | Shell_1181 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.774 |
| ADI32282.1 | uppS | Shell_1182 | Shell_1211 | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.636 |
| ADI32284.1 | ADI32282.1 | Shell_1184 | Shell_1182 | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | 0.661 |
| ADI32284.1 | rpoK | Shell_1184 | Shell_1183 | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.787 |
| ADI32284.1 | topA | Shell_1184 | Shell_1181 | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.607 |
| pyrH | ADI32282.1 | Shell_0016 | Shell_1182 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | 0.423 |
| pyrH | topA | Shell_0016 | Shell_1181 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.456 |
| pyrH | uppS | Shell_0016 | Shell_1211 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.764 |
| rpoK | ADI32282.1 | Shell_1183 | Shell_1182 | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | 0.857 |
| rpoK | ADI32284.1 | Shell_1183 | Shell_1184 | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | 0.787 |
| rpoK | topA | Shell_1183 | Shell_1181 | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.807 |
| topA | ADI32282.1 | Shell_1181 | Shell_1182 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | PFAM: peptidase M50; KEGG: scl:sce1715 integral membrane protease. | 0.774 |
| topA | ADI32284.1 | Shell_1181 | Shell_1184 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | 0.607 |
| topA | pyrH | Shell_1181 | Shell_0016 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.456 |
| topA | rpoK | Shell_1181 | Shell_1183 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.807 |