Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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uppSUndecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (269 aa)    
Predicted Functional Partners:
ADI31441.1
PFAM: Polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
 
 0.990
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.698
ADI31306.1
PFAM: putative RNA methylase; THUMP domain protein; methyltransferase small; KEGG: similar to THUMP domain containing 3.
   
    0.685
ADI31705.1
KEGG: dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.673
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.671
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.647
ADI31228.1
Hypothetical protein.
  
    0.645
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
    0.645
ADI32508.1
Hypothetical protein.
      
 0.618
ADI31768.1
UDP-N-acetylglucosamine--dolichyl-phosphateN- acetylglucosaminephosphotransferase; KEGG: N-acetylglucosamine-1-phosphate transferase; K01001 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphstransferase; PFAM: Glycosyl transferase, family 4, conserved region.
  
  
 0.608
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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