Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32320.1Dephospho-CoA kinase-like protein; KEGG: hypothetical protein; Belongs to the UPF0200 family. (192 aa)    
Predicted Functional Partners:
ADI32319.1
PFAM: Protein of unknown function DUF54; Belongs to the UPF0201 family.
 
    0.917
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
     0.745
ADI32323.1
KEGG: nis:NIS_1524 hypothetical protein.
 
     0.720
ADI32321.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.695
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
   0.546
ADI31859.1
PFAM: SMC domain protein; KEGG: viral A-type inclusion protein.
  
    0.503
ADI32269.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.503
ADI32174.1
KEGG: sat:SYN_02177 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein.
 
 
 0.491
cmk
Cytidylate kinase; KEGG: gem:GM21_1911 transport-associated protein; TIGRFAM: cytidylate kinase.
  
     0.480
ADI32578.1
PFAM: peptidase A24A prepilin type IV; Peptidase A24B, FlaK domain protein.
  
  
 0.480
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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