Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI32430.1TIGRFAM: tRNA intron endonuclease; KEGG: tRNA intron endonuclease family protein; PFAM: tRNA intron endonuclease, catalytic domain protein; tRNA intron endonuclease domain protein. (182 aa)    
Predicted Functional Partners:
ADI32562.1
PFAM: tRNA intron endonuclease, catalytic domain protein; tRNA intron endonuclease domain protein.
  
 
 
 0.911
ADI32429.1
KEGG: afw:Anae109_4377 hypothetical protein.
       0.863
ADI32431.1
Hypothetical protein.
       0.686
ADI31318.1
GTPase or GTP-binding protein-like protein; KEGG: AAA family ATPase Grc3 (predicted); K06947.
    
 0.668
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.612
ADI32428.1
Radical SAM domain protein; KEGG: pub:SAR11_0383 tRNA-i(6)A37 modification enzyme; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.577
ADI32662.1
PFAM: Protein of unknown function DUF1512.
  
     0.577
rtcB
PFAM: protein of unknown function UPF0027; KEGG: pca:Pcar_0019 hypothetical protein; Belongs to the RtcB family.
     
 0.572
ADI31216.1
SMART: Nucleotide binding protein PINc; KEGG: predicted protein; K11883 RNA-binding protein NOB1.
 
  
 0.532
ADI31721.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: Oligosaccharyl transferase STT3 subunit family protein.
  
     0.507
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.