Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI32439.1Amidohydrolase-like protein; KEGG: tdn:Suden_0602 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. (311 aa)    
Predicted Functional Partners:
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
       0.880
ADI32440.1
Hypothetical protein.
       0.876
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.687
ADI32437.1
KEGG: rlg:Rleg_5760 putative circadian clock protein, KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding; Belongs to the UPF0273 family.
       0.583
ADI31438.1
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nme:NMB1476 glutamate dehydrogenase, NAD-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.451
ADI31863.1
KEGG: bch:Bcen2424_6241 cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding.
    
 0.446
ADI32436.1
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; KEGG: rlg:Rleg_7058 AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein.
       0.446
pstB
ABC transporter related protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
   
  
 0.400
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.