| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI31181.1 | gcvH | Shell_0029 | Shell_1357 | KEGG: erg:ERGA_CDS_02460 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.577 |
| ADI31181.1 | gcvPB | Shell_0029 | Shell_1352 | KEGG: erg:ERGA_CDS_02460 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.509 |
| ADI31181.1 | glyA | Shell_0029 | Shell_1356 | KEGG: erg:ERGA_CDS_02460 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| ADI31181.1 | guaA | Shell_0029 | Shell_0033 | KEGG: erg:ERGA_CDS_02460 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.979 |
| ADI31410.1 | ADI31411.1 | Shell_0272 | Shell_0273 | KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | KEGG: avn:Avin_07410 phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.920 |
| ADI31410.1 | glyA | Shell_0272 | Shell_1356 | KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
| ADI31410.1 | guaA | Shell_0272 | Shell_0033 | KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.671 |
| ADI31411.1 | ADI31410.1 | Shell_0273 | Shell_0272 | KEGG: avn:Avin_07410 phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. | 0.920 |
| ADI31411.1 | glyA | Shell_0273 | Shell_1356 | KEGG: avn:Avin_07410 phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.948 |
| ADI32211.1 | ADI32445.1 | Shell_1108 | Shell_1354 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | 0.914 |
| ADI32211.1 | gcvH | Shell_1108 | Shell_1357 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.900 |
| ADI32211.1 | gcvPA | Shell_1108 | Shell_1353 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.902 |
| ADI32211.1 | gcvPB | Shell_1108 | Shell_1352 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.913 |
| ADI32211.1 | glyA | Shell_1108 | Shell_1356 | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| ADI32445.1 | ADI32211.1 | Shell_1354 | Shell_1108 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. | 0.914 |
| ADI32445.1 | gcvH | Shell_1354 | Shell_1357 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| ADI32445.1 | gcvPA | Shell_1354 | Shell_1353 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| ADI32445.1 | gcvPB | Shell_1354 | Shell_1352 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
| ADI32445.1 | glyA | Shell_1354 | Shell_1356 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
| ADI32445.1 | guaA | Shell_1354 | Shell_0033 | KEGG: pub:SAR11_0666 glycine cleavage system protein T2; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.650 |