Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (261 aa)    
Predicted Functional Partners:
ADI32023.1
PFAM: beta-lactamase domain protein; KEGG: dat:HRM2_43600 putative metal-dependent hydrolase.
    
  0.902
ADI32396.1
PFAM: beta-lactamase domain protein; KEGG: dat:HRM2_43600 putative metal-dependent hydrolase.
    
  0.902
ADI32418.1
PFAM: beta-lactamase domain protein; KEGG: dat:HRM2_43600 putative metal-dependent hydrolase.
    
  0.902
ADI32462.1
PFAM: flavoprotein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mfa:Mfla_1582 flavoprotein.
 
     0.843
ADI32460.1
Hypothetical protein.
       0.652
ADI32464.1
PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198.
 
   
 0.555
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.497
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.495
ADI31216.1
SMART: Nucleotide binding protein PINc; KEGG: predicted protein; K11883 RNA-binding protein NOB1.
  
     0.466
ADI31933.1
Hypothetical protein; KEGG: mca:MCA1245 pterin-binding domain-containing protein.
 
   
 0.404
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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