Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32464.1PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198. (283 aa)    
Predicted Functional Partners:
ADI31932.1
Radical SAM domain protein; KEGG: shl:Shal_0144 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB.
     
  0.900
ADI32486.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dvm:DvMF_1473 anaerobic ribonucleoside triphosphate reductase.
  
  
  0.836
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.803
ADI32370.1
Adenylyl cyclase CyaB; KEGG: dal:Dalk_3154 adenylate cyclase; TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase.
     
  0.800
ADI32463.1
Butyrate kinase-like protein; KEGG: pca:Pcar_2852 butyrate kinase.
 
     0.800
ADI32465.1
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aap:NT05HA_0382 queuosine biosynthesis protein QueD.
     
 0.707
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
 
   
 0.555
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
   
 0.529
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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