Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32465.1PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: aap:NT05HA_0382 queuosine biosynthesis protein QueD. (137 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.709
ADI32464.1
PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198.
     
 0.707
ADI32463.1
Butyrate kinase-like protein; KEGG: pca:Pcar_2852 butyrate kinase.
       0.557
cysS
KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia DALR.
  
  
 0.554
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
   
 
 0.533
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
   0.529
ADI31327.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: atc:AGR_C_1817 3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.506
tgtA
tRNA-guanine transglycosylase, various specificities; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
   
 
 0.417
thrS
KEGG: dvl:Dvul_0707 threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; Anticodon-binding domain protein; tRNA synthetase class II (G H P and S); Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.411
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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