STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI32486.1TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dvm:DvMF_1473 anaerobic ribonucleoside triphosphate reductase. (631 aa)    
Predicted Functional Partners:
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
    
 0.960
ADI32487.1
KEGG: nis:NIS_1769 hypothetical protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein.
 
  
 0.938
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.920
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.918
ADI32300.1
Protein of unknown function DUF265; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
   
 
  0.908
ADI32370.1
Adenylyl cyclase CyaB; KEGG: dal:Dalk_3154 adenylate cyclase; TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase.
     
  0.900
ADI32655.1
TIGRFAM: pyruvate kinase; KEGG: pca:Pcar_2983 pyruvate kinase; PFAM: Pyruvate kinase barrel; Belongs to the pyruvate kinase family.
     
  0.900
ADI32464.1
PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198.
  
  
  0.836
ADI31932.1
Radical SAM domain protein; KEGG: shl:Shal_0144 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB.
    
 0.826
gch3
GTP cyclohydrolase IIa; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
     
  0.800
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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