STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkCytidylate kinase; KEGG: gem:GM21_1911 transport-associated protein; TIGRFAM: cytidylate kinase. (177 aa)    
Predicted Functional Partners:
rpl34e
PFAM: Ribosomal protein L34e; KEGG: similar to putative ribosomal protein L34; K02915 large subunit ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
 
    0.972
rpl14e
KEGG: hypothetical protein; K02875 large subunit ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family.
  
    0.968
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.935
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
    0.911
rps4e
KEGG: RPS4; ribosomal protein S4, component of cytosolic 80S ribosome and 40S small subunit; K02987 small subunit ribosomal protein S4e; PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.910
rpl5
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
    0.904
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.903
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
    0.903
ADI31206.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
ADI32095.1
AMP phosphorylase; KEGG: tau:Tola_2482 thymidine phosphorylase; TIGRFAM: AMP phosphorylase; thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like.
     
  0.900
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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