STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl5Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (188 aa)    
Predicted Functional Partners:
rpl21e
PFAM: Ribosomal protein L21e; KEGG: hypothetical protein; K02889 large subunit ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
   
 0.999
rpl40e
PFAM: Ribosomal protein L40e; KEGG: Ubiquitin/ribosomal protein CEP52; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.999
rpl10e
KEGG: 60S ribosomal protein L10; K02866 large subunit ribosomal protein L10e; TIGRFAM: ribosomal protein L10.e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family.
  
 0.999
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
   
 0.999
rpl35ae
KEGG: hypothetical protein; K02917 large subunit ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family.
   
 0.999
rpl13e
Rpl13; K02873 large subunit ribosomal protein L13e; KEGG: rpl13; ribosomal protein L13; K02873 large subunit ribosomal protein L13e; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 0.999
ADI32347.1
Hypothetical protein.
   
 
 0.999
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
 
 0.999
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.999
rpl1
Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 0.999
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.