Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI32562.1PFAM: tRNA intron endonuclease, catalytic domain protein; tRNA intron endonuclease domain protein. (173 aa)    
Predicted Functional Partners:
ADI32430.1
TIGRFAM: tRNA intron endonuclease; KEGG: tRNA intron endonuclease family protein; PFAM: tRNA intron endonuclease, catalytic domain protein; tRNA intron endonuclease domain protein.
  
 
 
 0.911
hisS
TIGRFAM: histidyl-tRNA synthetase; KEGG: rak:A1C_02295 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.880
rtcB
PFAM: protein of unknown function UPF0027; KEGG: pca:Pcar_0019 hypothetical protein; Belongs to the RtcB family.
     
 0.723
ADI31318.1
GTPase or GTP-binding protein-like protein; KEGG: AAA family ATPase Grc3 (predicted); K06947.
    
 0.668
ADI32560.1
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
       0.649
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.604
ADI32561.1
PFAM: protein of unknown function DUF996; KEGG: cco:CCC13826_0803 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
       0.542
dtdA
Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
   
 0.467
ADI31216.1
SMART: Nucleotide binding protein PINc; KEGG: predicted protein; K11883 RNA-binding protein NOB1.
  
  
 0.462
ADI32319.1
PFAM: Protein of unknown function DUF54; Belongs to the UPF0201 family.
 
     0.444
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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