STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
albADNA-binding protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (98 aa)    
Predicted Functional Partners:
ADI32585.1
PFAM: Alba, DNA/RNA-binding protein.
  
 
  
0.814
rgy-2
DNA topoisomerase (ATP-hydrolyzing); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
       0.649
ADI31172.1
PFAM: Protein of unknown function DUF655.
  
     0.579
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.535
ADI32610.1
KEGG: snrnp sm protein; PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein.
  
   
 0.471
ADI31155.1
PFAM: protein of unknown function DUF99; KEGG: tgr:Tgr7_2677 protein of unknown function DUF99; Belongs to the UPF0215 family.
  
     0.470
rpl18e
PFAM: ribosomal protein L15; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.436
ADI31860.1
KEGG: pfs:PFLU0171 hypothetical protein.
  
     0.429
ADI31549.1
TIGRFAM: ZPR1-related zinc finger protein; ZPR1-like zinc finger protein; PFAM: ZPR1-type Zinc finger domain protein; KEGG: ZNF259; zinc finger protein 259; K06874; SMART: ZPR1-type Zinc finger domain protein.
  
     0.428
ADI31228.1
Hypothetical protein.
 
     0.403
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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