STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egsA3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (354 aa)    
Predicted Functional Partners:
ADI32556.1
Geranylgeranylglyceryl phosphate synthase family protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.935
ADI31686.1
PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sat:SYN_02446 glycerol-3-phosphate dehydrogenase.
    
  0.902
psmB
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
     0.729
ADI32395.1
PFAM: class II aldolase/adducin family protein; KEGG: pca:Pcar_3030 L-fuculose-1-phosphate aldolase.
 
  
 0.603
ADI31887.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: dma:DMR_08290 alcohol dehydrogenase.
 
  
 0.576
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
   
 0.539
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
  
  
 0.513
srp19
Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
  
   
 0.502
ADI32238.1
HAD-superfamily hydrolase, subfamily IIA; KEGG: hypothetical protein; K01101 4-nitrophenyl phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
  
 0.501
ADI32573.1
PFAM: extracellular solute-binding protein family 1; KEGG: dde:Dde_3657 sugar ABC transporter, substrate-binding protein.
 
  
 0.439
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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