STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (210 aa)    
Predicted Functional Partners:
psmB-2
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
  
 
0.907
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
 0.897
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.867
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.847
ADI31615.1
KEGG: hypothetical protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
  
 0.835
rpl40e
PFAM: Ribosomal protein L40e; KEGG: Ubiquitin/ribosomal protein CEP52; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.789
egsA
3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
 
     0.729
ADI31622.1
KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein.
    
 0.685
ADI32616.1
KEGG: scl:sce4166 hypothetical protein; TIGRFAM: KH-domain/beta-lactamase-domain protein; PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase.
     
 0.675
ADI31223.1
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; KEGG: gur:Gura_2842 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein.
  
 0.620
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.