Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADI32647.1Thermosome; KEGG: hypothetical protein; K09497 T-complex protein 1 subunit epsilon; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. (543 aa)    
Predicted Functional Partners:
ADI31622.1
KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein.
   
 0.857
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.808
ADI32284.1
Thermosome; KEGG: tcp1; t-complex polypeptide 1; K09493 T-complex protein 1 subunit alpha; TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1.
    
   0.757
rps2
Ribosomal protein S2; KEGG: expressed hypothetical protein; K02998 small subunit ribosomal protein SAe; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 0.748
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
 
 0.726
tbp
TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
 
 
 0.718
psmA
Proteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 
 0.715
ADI32476.1
Prefoldin, alpha subunit; KEGG: AGAP003416-PA; K04797 prefoldin alpha subunit; TIGRFAM: prefoldin, alpha subunit; PFAM: Prefoldin alpha domain protein.
   
 0.714
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.701
ADI31845.1
PFAM: Aldehyde Dehydrogenase; KEGG: geo:Geob_3547 aldehyde dehydrogenase.
   
 0.697
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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